What happens in the body with arteriosclerosis?

Limits to blood flow: In arteriosclerosis, cholesterol builds up in the walls of the artery compromising the inside of the artery where blood flows. The end result can be limitations in blood flow to the brain, heart, intestines, kidney, and extremities. The symptoms are particular to the organ affected.

Clogs and clots: The arteries become clogged, clotted, and occluded and the result is stroke, heart attack, or gangrene (depending on the location).