Get Virtual Care
For Businesses
About Us
A member asked:
If i have an elevated crp and est with a negative ana what could this indicate? i have type 1 dm and fibromyalgia. they were suspecting lupus
A doctor has provided 1 answer
The : The ESR and CRP are both markers of inflammation. However, they are very non-specific and can be elevated in a wide variety of conditions including infections, malignancies, and auto-immune diseases. The ANA is the screening test for lupus and similar conditions. It has many false positives but very few false negatives. In your case, the negative ANA most likely means that you elevated ESR and CRP are not due to lupus.
Answered 10/3/2016
5.3k views
Related Questions
A member asked:
Can you have lupus with completely normal bloodwork? ANA, ENA neg, Complement levels normal, CBC normal. ESR of 2 and normal CRP
A doctor has provided 1 answer
A member asked:
I had ANA 1:160+ , ESR 29 CRP 0.1 autoantibodies show ssa of 8 (0-40 is neg) and scl-70 ENA ab of 3 (0-40 is neg) wouldn't this be scleroderma? Not lupus? Why would lupus patient have scl-70 markers?
5 doctors weighed in across 2 answers
A member asked:
Lupus or RA? Positive ANA 1:160, Speckled, Homogeneous; Neg ENA, Anti-DNA, & RF; High ESR, CRP, Ab IgG, 14-3-3 eta, & Leukocyte Esterase; Low Lymphocy
A doctor has provided 1 answer
A member asked:
When lupus is being treated with plaquenil (hydroxychloroquine) does crp, ESR go down & does positive ANA turn negative?
A doctor has provided 1 answer
A member asked:
Ana direct positive ANA , ifa neg , rnp 2.3, CRP 5.4 ss-b2.7.Diag with lupus connective tissue and sjorgen all at once? Why 2 ANA tests different answ
A doctor has provided 1 answer
People also searched for:
My ANA was negative. Is it possible to still have RA, Lupus, or Fibromyalgia?Lyrica (pregabalin) is NOT helping the leg/arm/hand/foot pain. CRP is 6.5.
Weak positive Histone Antibody, negative ANA, elevated sed rate, elevated C-reactive protein. Elevated White blood cell. Doctor says its nothing. I believe signs point to drug induced lupus. What could this be? What causes positive Histone antibody?
Could fibromalagia cause ANA positive? 1:640 speckled and sed rate elevated? Lupus panel negative
Do i have lupus ? posisitve ana with a titer of 1:40 homogenous plus a elevated crp level 1.2 also protein in the urine .
Diagnosed w/lupus 10 years ago &have been on plaqunenil. For past 6 years, my SED rate, c3, c4, and crp have been normal.my double stranded dna has been always negative. I have Ana 1:640 and other qualifying symptoms. Do I no longer have lupus ?
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Download HealthTap
Video visit and message your doctor
