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A 48-year-old female asked:

Can tylenol (acetaminophen) with codeine show as coke in a drug test my sister in law to a drug test, she was taking tylenol (acetaminophen) with codeine, the test came out positive for cocaine, can this happen?

3 doctor answers4 doctors weighed in
Dr. Laura McMullen
Pediatrics 22 years experience
Codeine : Codeine is in the opiate class of drugs such as heroin, oxycodone, and morphine so it would cause a drug test to be positive for opiates. Codeine would not cause a test to be positive for cocaine.
Dr. Adam Front
Clinical Psychology 28 years experience
Not likely: Most drug tests use a first test, TLC or thin layer chromatography, as an initial screen. This test is prone to cross-reaction or "false positive" results for some substances. Usually if the TLC is positive, a second test, gcms or gas chromatography mass spectroscopy is used to confirm. This test is much more specific for specific molecules and not likely to yield false positive results.
Dr. Bahman Omrani
Pain Management 18 years experience
Cocaine is cocaine: If Cocaine is positive on a confirmatory urine drug screen (e.g.Lc/ms), 99.99% it is cocaine. Specificity for both screening & confirmatory urine tests for Cocaine is very high, thanks to its unique molecular structure. Even similar substances in the -caine class such as lidocaie, marcaine, etc. Do not cause a false positive Cocaine on a urine drug screen.

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Jeannette, PA
A member asked:

Can tylenol (acetaminophen) with codeine show as coke in a drug test my sister in law to a drug test, she was taking tylenol (acetaminophen) with code?

1 doctor answer1 doctor weighed in
Dr. Richard Zimon
Internal Medicine 60 years experience
NOT: AS "COKE" (I assume you mean Cocaine..BUT a POSITIVE TEST for OPIATES will result! Hope this helpos! Dr Z
Last updated Dec 19, 2017

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