What classes of medications are helpful to treat or control pulmonary hypertension?

Drugs: There are 3 classes of meds currently approved for pulmonary htn. They are endothelin receptor antagonists (tracleer and letairis), pde-4 inhibitors (revatio and adcirca) and prostacyclin analogs (remodulin, flolan, ventavis, (iloprost) and tyvaso). There are other drugs in other classes still under development.

Depends on the cause: There are multiple causes of pulmonary hypertension and based on the cause the treatment should be focused. For group 1 pulmonary hypertension that is caused by idiopathic hypertension (unknown cause) and a positive vasoreactivity test (test to see if the disease responds to the vasodilators) then some vasodilators can be given.

PH Cure: There are 9 available medications for pulmonary arterial hypertension (pah) including phosphodiesterase-5 inhibitors, endothelin receptor blockers and prostaclins. The treatment can be quite effective but does not generally cure pah. Lung transplant can cure the disease but has other significant issues.