What is the typical treatment for invasive colorectal and pancreatic cancer?

Chemo: Generally an exploration will have been needed to establish the extent of these cancers and if found to be widespread, chemotherapy is the best course to prolong life and prevent further spread.

Multi-modal-Sx.Cx.Rx: Treatment for these cases is likely multimodal, like surgery, chemo., and radiation. Specifically, the treatment for advanced/invasive colon cancer is radiation and chemo., like 5-fu (5 fluorouracil) and folinic acid to at least palliate symptoms. Pancreatic cancer has a whipple procedure, that removes parts of the duodenum, pancreas, and bile ducts in localized cases and gemcitabine if advanced.

Depends on stage: Colon ca: stage 1 (surgery, no chemo), stage 2 (surgery, usually no chemo), stage 3 (surgery, chemo), stage 4 (chemo, surgery and radiation only for symptom control). Pancreas staging is often defined functionally as "resectable" (surgery as primary treatment), "borderline/unresectable" (neo-adjuvant chemo and surgery if possible), advanced/metastatic (chemo). Details too advanced for answer limit.