A member asked:

Has a duchenne muscular dystrophy chromosome map been done yet?

4 doctors weighed in across 2 answers
Dr. Eric Bluman answered

Specializes in Orthopedic Foot and Ankle Surgery

Genetics: The molecular biology of dmd has been fairly well investigated at this time. The gene responsible for the disease codes for a mutated form of the protein called dystrophin. This gene is located on the x-chromosome. For more information on this go to http://www.Ncbi.Nlm.Nih.Gov/pubmedhealth/pmh0001724/.

Answered 12/5/2012

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Dr. Johanna Fricke answered

Specializes in Pediatrics - Developmental and Behavioral

A single gene : Disorder, dmd is caused by a mutation in the x-linked dmd gene, xp21.1, causing absence of dystrophin, a muscle protein. Deletions in a specific part of the dystrophin gene are associated with cognitive impairment, especially in verbal memory & auditory comprehension. There's also some increased risk of adhd & autistic disorder. See www.Ncbi.Nlm.Nih.Gov/omim, online mendelian inheritance in man.

Answered 12/5/2012

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