A member asked:

What are some of the of non genetic or "acquired" mitochondrial disease?

3 doctors weighed in across 2 answers

Heavy metals: Lead and mercury toxicity, prolonged immobilization and lack of exercise, etc. - those are forms of secondary mitochondrial disease.

Answered 12/31/2014

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A few examples: The most common acquired mitochondrial disorder is aging. Other causes include medications or toxins that impair mitochondrial function. Concussion at the cellular level is a temporary impairment of mitochondrial function and the same impairment at the cellular level can occur with stroke. The accumulation of abnormal substances in the cell in Alzheimer disease also damages mitochondrial function

Answered 4/21/2020

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