Is there a relation between avascular necrosis and multiple sclerosis?

Yes, But...: Relapses due to multiple sclerosis need treatment, and most commonly we use high dose steroids or acth to reverse the process. In an occasional patient the steroids can cause adverse event, avascular necrosis of hip, shoulder, or knee. This can damage the joint profoundly, with need for joint replacement. Ms doesn't cause on its own.