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A 48-year-old member asked:

What is the difference between actonel (risedronate) and fosamax?

3 doctor answers2 doctors weighed in
Dr. Frederick Singer
Endocrinology 59 years experience
Chemical structure: Actonel (risedronate) and Fosamax are drugs in the bisphosphonate family. They have similar but not identical structures. They produce similar benefits for osteoporosis patients.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Arthur Heller
Gastroenterology 44 years experience
Similar, but differ: Both are bisphosphonate drugs, taken orally, which decrease bone breakdown by osteoclast cells, and therefore increase bone density (a marker of bone strength). Different dosing, but can be weekly or monthly for either in osteoporosis. Were used in tumors to or to bone-now drugs mostly given IV for that. Fosamax (alendronate) stays in the system and bone longer; was thought to be more GI irritating (maybe not).
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Arthur Heller
Gastroenterology 44 years experience
Similar, but differ: Both are bisphosphonate drugs, taken orally, which decrease bone breakdown by osteoclast cells, and therefore increase bone density (a marker of bone strength). Different dosing, but can be weekly or monthly for either in osteoporosis. Were used in tumors to or to bone-now drugs mostly given IV for that. Fosamax (alendronate) stays in the system and bone longer; was thought to be more GI irritating (maybe not).
Created for people with ongoing healthcare needs but benefits everyone.

Similar questions

A 48-year-old member asked:

Which is better: actonel (risedronate) vs fosamax?

1 doctor answer1 doctor weighed in
Dr. Paul Grin
Pain Management 37 years experience
No difference: There is no such thing as "best" or "worst" medication, only those that work and don't work, based on the patient's individual circumstances and genetics.
Created for people with ongoing healthcare needs but benefits everyone.
A 29-year-old member asked:

What is the difference between actonel (risedronate) and fossamax?

1 doctor answer1 doctor weighed in
Dr. Arthur Heller
Gastroenterology 44 years experience
Similar, but differ: Both are bisphosphonate drugs, taken orally, which decrease bone breakdown by osteoclast cells, and therefore increase bone density ;#40;a marker of bone strength;#41;. Different dosing, but can be weekly or monthly for either in osteoporosis. Were used in tumors in or to bone-now drugs mostly given IV for that. Fosamax (alendronate) stays in the system and bone longer; was thought to be more GI irritating ;#40;maybe not;#41;.
Created for people with ongoing healthcare needs but benefits everyone.
CA
A 23-year-old female asked:

Which is stronger: actonel (risedronate) or fosamax?

1 doctor answer5 doctors weighed in
Dr. David Sneid
Endocrinology 42 years experience
Neither is: really "stronger". There are slight differences depending upon what criteria you use, but both are very potent and very effective inhibitors of bone resorption. Both need to be taken as directed, and combined with adequate calcium and vitamin D3.
Created for people with ongoing healthcare needs but benefits everyone.
A 34-year-old member asked:

Is there a generic drug equivalent for Fosamax or actonel (risedronate)?

1 doctor answer1 doctor weighed in
Dr. Ankush Bansal
Internal Medicine 15 years experience
Yes & no: Fosamax is off patent - the generic is alendronate. Generics are absolutely as effective as the brand name. Actonel (risedronate) is still on patent. No generic form exists yet.
Created for people with ongoing healthcare needs but benefits everyone.

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Last updated Dec 18, 2018
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