What are the causes of achondroplasia?

New mutation: Most cases arise from a new mutation to normal parents. It can also be transmitted in autosomal dominant fashion if parent (s) are affected by same condition.

Mostly random: Most cases arise from a new mutation to normal parents. Achondroplasia is inherited in autosomal dominant fashion as well. Therefore, couples with achondroplasia marries, they have a 25% risk of transmitting their condition , homozygous achondroplasia , to each offspring.