Can a broken ankle cause peripheral vascular disease?

Not really: Not really. Pvd is most commonly caused by atherosclerosis. The injury which caused the fracture could also have caused injury to the arteries. We see this in patients who have been in car accidents or dislocate their knee.

Not likely: Peripheral vascular (arterial) disease (pad) is a more generalized problem than would be caused by a localized injury like a broken ankle. High blood pressure, smoking, obesity, high cholesterol, diabetes, and the like are far more likely causes for pad than a broken ankle would be.

Unlikely: It could cause local disruption of some vessels so that you could get permenent swelling of that ankle but not so much the "traditional" PVD associated with diseases like diabetes or smoking.