A member asked:

How can i stop taking pristiq (desvenlafaxine) without withdrawls?

10 doctors weighed in across 5 answers

Talk to your doctor: Stopping antidepressants can be easy for some but horrible for others. The best thing to do is talk with your doctor for a plan in weaning down. There is no one size fits all solution.

Answered 2/9/2014

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Dr. Pamela Pappas answered

Specializes in Psychiatry

More than 1 issue: Stopping Pristiq (desvenlafaxine) is best done by tapering with your physician's guidance, as dr. Larsh recommends. But it's very important to be sure that the prescribed-for condition is no longer a problem, first. In many people, depression is a long-standing or recurrent condition. For these, medication is often used in a preventative way. Best thing is a good relationship with your doctor, & working together.

Answered 6/30/2014

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Taper or switch: Suddenly stopping short half life ssri (paxil) & snri (pristiq, effexor, (venlafaxine) cymbalta) antidepressants after long term treatment with them (regardless of whether treatment was successful) can be miserable. Stopping should be supervised by a physician. The simplest is to switch to Prozac (which has an extremely long half-life) for a few days then if there are no problems, stop the prozac.

Answered 6/30/2014

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Pristiq (desvenlafaxine): Pristiq (desvenlafaxine) belongs to a group of meds called ssri. In order to avoid withdrawal it has to be weaned off during 4-6 weeks, slowly increasing the amount of days that you do not take it, for instance, within 2 weeks to take it every other day, then within 2 weeks to take it every 3 days, e.C.

Answered 10/3/2016

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Dr. Alan Ali answered

Specializes in Psychiatry

Pristiq (desvenlafaxine): Work with your doctor on plan to gradually taper and monitor for withdrawal or recurrence of symptoms.

Answered 9/19/2019

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