Why is amputation needed for some diabetics?

Low blood flow: Calcification & narrowing or blockage of the very smallest arteries results in low blood flow, low oxygen, and low nutrition to the site. Most common affected are feet & toes. Low blood flow, tissue trauma, skin ulcer formation & infections result in infected, dead, or gangrenous tissue at the site. Serious infections or gangrenous tissue can lead to amputation if unable to be corrected or healed.

Low flow / infection: Poor circulation and infection are two factors that contribute to the need for an amputation in diabetic patients.