Probably not, unless: You are a very young child with pku and can't metabolize phenylalanine, or you have an unusual sensitivity to artificial sweeteners, or you are drinking many sodas a day because you are sleep deprived. A search of pubmed did not turn up any evidence of memory loss from diet sodas. There are many rumors to the contrary, but most are unsupported.
Answered 5/11/2016
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