How does damage to the musculoskeletal system cause ischemia?

Musculoskeletal syst: Damage to muscle may cause an elevation of creatine kinase. Ischemia and damage of the heart muscle may cause elevation of a subtraction if creatine kinase that is mb subtraction. Sometimes the mb subtraction may be elevated with high levels of total ck with muscle damage with interpretation of treating health workers that cardiac ischemia cannot be ruled out.