What drugs are used for fluid retention?

Diuretics.: Fluid retention can have many different causes, but one strategy is to treat with diuretics. These drugs act on the kidney to help eliminate fluid by increasing urine production. Lasix (furosemide) is a common diuretic, one of several types. Thiazides (hctz), carbonic anhydrase inhibitors (acetezolamide), potassium sparing diuretics (spironolactone), & osmotic diuretics (mannitol) are examples.