A member asked:

Why are sclera blue in osteogenesis imperfecta?

2 doctors weighed in across 2 answers

Thinner sclera: The white part of the eyeball is the sclera. In osteogenesis imperfecta, the person has a genetic mutation that causes him to make defective connective tissues and/or not enough connective tissues. The eyeball sclera is made of connective tissue, but it is thinner in an o.I. Person, so it looks bluish instead of white.

Answered 11/26/2018

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Blue sclera: The thinner scleral outer wall allows some transmission of the darker inner color giving a sensation of blue.

Answered 2/1/2012

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