Can osteogenesis imperfecta be detected prior to birth?

Sometimes: It depends on the type of oi. If a parent has oi, and the genetic mutation they carry has been identified, the fetal dna can be checked for the same mutation. This is done through amniocentesis and chorionic villus sampling. Sometimes fetal ultrasound can show changes of oi in severe cases.

Possible : Possible with amniocentesis but i defer to geneticist.