Degenerative disease: A large group of sporadic and inherited disorders with symptom onset in the 5th decade of life. Main manifestations include ataxia, first in the legs then arms, hands and facial muscles.Characterized by extensive degeneration of the cerebellum, pontine nuclei and medullary olivary nuclei, opca's have been described with many other clinical findings. Treatment is symtom specific and variable.
Answered 9/28/2016
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