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A 47-year-old member asked:

Is it safe to take nabumetone with ibuprofen for pain?

2 doctor answers6 doctors weighed in
Dr. Larry Stephenson M D
Neurology 45 years experience
Should avoid : Nsaids increase the liklihood of complications including GI probs including gastric ulcer and GI bleeding. May also inc the liklihood aggrevation of blood pressure, renal, and liver dysfunction.
Dr. Ricardo Alvillar
Rheumatology 44 years experience
Not together: Taking two non-steroidal anti-inflammatory drugs can cause gastritis, gastric ulcer, including gastric perforation. So, in general , the answer is no. On the other hand, assumning a single dose of Ibuprofen (800mg), with its half-life of nearly two hours, should be "completely" eliminated in 10 hours. Nabumetone, however, has a half-life of 20-24 hours is not "completely" elimininated for 5 day.

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Last updated Feb 28, 2020

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