A 38-year-old member asked:
What is the genetic recurrence of breast cancer?
1 doctor answer • 3 doctors weighed in

Dr. Barry Rosenanswered
General Surgery 36 years experience
10-15% Hereditary: We believe that only 10-15% of breast cancers are hereditary, with the rest being environmental in origin. People w/the hereditary form of breast cancer tend to get diagnosed earlier in life and may get cancer in both breasts. When treated by lumpectomy or (single) mastectomy, it is not uncommon to develop a second, unrelated breast cancer; therefore, many opt for double mastectomies.
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5.7k viewsReviewed >2 years ago
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CA
A 40-year-old member asked:
Is dcis breast cancer genetic?
4 doctor answers • 18 doctors weighed in

Dr. Devon Websteranswered
Medical Oncology 24 years experience
It can be: Dcis, the earliest form of breast cancer, can be associated with brca mutations. 13% of women under 50 diagnosed with dcis had a brca mutation in retrospective (looking backwards) studies. Women with a family history of breast or ovarian cancer or dcis before age 50 should have genetic counseling. For more info:
http://clincancerres.Aacrjournals.Org/content/13/14/4306.Full.
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6.3k viewsReviewed >2 years ago
A 36-year-old member asked:
What is the likelihood of breast cancer recurrence?
2 doctor answers • 4 doctors weighed in

Dr. Barry Rosenanswered
General Surgery 36 years experience
Variable.: Breast cancer may recur either in the breast ("local recurrence") or elsewhere in the body (distant metastasis). The risk of metastasis varies from very low to high, and is correlated with the stage of the cancer; the stage is associated with the size of the cancer and lymph node involvement. Local recurrence following lumpectomy and radiation therapy is less than 5%.
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A 41-year-old member asked:
Is breast cancer genetic or caused by the environment or both?
2 doctor answers • 3 doctors weighed in

Dr. Richard Orranswered
Surgical Oncology 46 years experience
Both: Only 10-20% of breast cancers are genetically related. We are not sure what causes the remainder, but environmental factors (such as the organochloride pesticides that were sprayed 30-50 years ago) are potentially responsible. Estrogen replacement is contributing to some, and the fact that women are living to be older with each generation increases the number of elderly breast cancer.
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5.6k viewsReviewed >2 years ago
A 40-year-old member asked:
I need your expertise, is breast cancer genetic?
1 doctor answer • 2 doctors weighed in

Dr. Heidi Fowleranswered
Psychiatry 27 years experience
Genetics can play a: Significant role for some women (not for others). Include: being female, increasing age, genetics, family history of breast cancer, previous breast cancer, being caucasian, dense breast tissue, some previous benign breast conditions, never having given birth or 1st child after age 30, early menarche, late menopause, radiation (chest), exposure to diethylstilbestrol, hormone replacement after >>.
Created for people with ongoing healthcare needs but benefits everyone.
4.7k viewsReviewed >2 years ago

Dr. Heidi Fowler commented
Psychiatry 27 years experience
Provided original answer
menopause, oral contraceptives, obesity, heavier alcohol use. Etc. If you have a family history for breast cancer you can have genetic studies performed.
Dec 17, 2013
A 43-year-old member asked:
What are the odds of a breast cancer recurrence?
2 doctor answers • 4 doctors weighed in

Dr. Upendra Parvathanenianswered
Radiation Oncology 30 years experience
Depends: Tumor factors - based on TNM staging, receptor status, grade etc
treatment factors - optimal therapy vs. Not
patient factors - genetic predisposition - this is rarely the issue
time factor - longer the time lapse since initial therapy, lesser the odds.
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5.6k viewsReviewed >2 years ago
Last updated Aug 18, 2012
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