How long will it take nicotene from cigarettes to get out of your system?

Variable: Depends what you mean by "out of system". Nicotine can clear within 2 days but its metabolic product from the liver-- "cotinine" --is cleared more slowly. Cotinine is often tested for in urine & blood tests and it can be found many days later, especially in heavy smokers. However, people experience nicotine withdrawal within a few hours & most nicotine suffering is very severe within 20 hours.