Can plavix (clopidogrel) lead to heartburn?

Just like aspirin: The risk of gastrointestinal complications from Plavix (clopidogrel) is similar to Aspirin and includes gastritis/peptic ulcers, bleeding. Diarrhea, rash, low platelet count etc... Aspirin can be more problematic to asthmatics, but otherswise both meds have similar side effects. Plavix (clopidogrel) is only marginally better than Aspirin in term of benefit, but costs muc much more. Use some prilosec. Consult doc. Good luck.