Is reperfusion injury?

Reperfusion injury: Reperfusion injury refers to tissue damage caused when blood supply returns to the tissue after a period of ischemia or lack of oxygen. The absence of oxygen and nutrients from blood during the ischemic period creates a condition in which the restoration of circulation results in leaking from blood vessel the substances that produce damage to tissue - the degraded enzymes create further damage.

Great Question!: Reperfusion injury is something that occurs when an organ or extremity is denied blood flow (perfusion) and subsequently blood flow is restored. At this point, without very specific therapy and monitoring, reperfusion injury can ensue. The cytotoxins are released at this point, with resultant cellular injury and apoptosis occurring. This can lead to limb or organ damage/loss.