How can you tell if someone has neurofibromatosis?

What type?: Nf-1 has classic skin manifestations - one just examines skin to see if criteria for the number/size of nevi and ash-leaf spots on the skin are seen.

Multiple lumps: The neurofibromas tend to be everywhere and visible, large brown spots are common"cafe au lait" spots. Some patients will also have pheochromocytoma there is a family tendency.

Many manifestations: Several signs of nf1, main one 6 or mor flat brown spots over 5 mm in greatest diameter in children and over 15 mm in greatest diameter in post-pubertal individuals, two or more soft nodules or neurofibromas or 1 plexiform neurofibroma, freckling in the axillary or groin regions, tumors of optic nerve, gliomas, bony abnormality such as scoliosis, bone overgrowth or congenital fracture.