A member asked:

What does "duchene muscular dystrophy" mean?

2 doctors weighed in across 2 answers

Genetic muscle issue: Dmd is a genetic disorder in which there is a mutation in dystrophin, a structural protein found in muscle cell membrane. It causes progressive weakness that typically starts in the legs and pelvis, but eventually spreads throughout the body and also compromises breathing. There are symptomatic treatments, but no cure.

Answered 2/23/2013

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Inherited disease: Progressive loss of muscle strength with high CPK and typical findings on muscle biopsy was well described by duchenne. The disorder seemed to begin in early childhood and progress to death by adolescence. It occurred in boys and was dominantly inherited. Dna markers and enzyme assays are now available to define the disorder. Treatment with steroids slows the process.

Answered 6/10/2014

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