Caffeine & antihist: It's ok to take them together. Vistaril is a brand name for hydroxyzine, the parent antihistamine of cetirizine. Hydroxyzine is a sedating antihistamine, and caffeine has some stimulant properties, so sometimes people who take sedating antihistamines use coffee intentionally to help offset the drowsiness it causes. This may or may not work for a particular person, depending on various factors.
Answered 2/7/2021
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