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A member asked:
How does hydralazine block the vagus nerve?
A doctor has provided 1 answer
Not a MOA: Hydralazine is a direct smooth muscle relaxer based on its intracellular action on Calcium. In situ, it does not appear to have a direct effect on the vagus nerve, but rather may have an effect on the sinoatrial node and a reflex response (increased heart rate) due to the decreased blood pressure (baroreceptor response).
Answered 5/1/2017
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