What is the best drugstore anti-acne wash/medication (otc)?

Get an Rx instead: Over-the-counter preparations do not work well. I start with topical Clindamycin with or without a retinoic acid derivative. If needed after a few weeks, consider adding an oral antibiotic such as Erythromycin or tetracycline / Minocycline as suitable for the individual. Dermatologists have the big guns -- accutane, lasers. Freedom from acne should be a person's right. Good luck.