What's the best time of day to take my allergy tablets?

Allergy meds: If your tablet is Allegra and it's non-sedating, you can take it anytime. Ideally, you'd like to take it 30-60 minutes before your allergy exposure, if there's a specific thing you react to. If you take benadryl, (diphenhydramine) best take it at night if it sedates you. If you take sudafed for congestion, avoid taking it at night because it causes insomnia. Prescription sprays, any time you want. Singular --night.