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A member asked:
How long does drowsiness generally last after a benadryl (diphenhydramine)?
A doctor has provided 1 answer
Four to six hours: The half life of Benadryl (diphenhydramine) is about four to six hours and usually the sedation will wear off within that time frame. As one continues to use it often a certain amount of tolerance develops and less sedation is appreciated. Studies have shown that its effect on brain function still continues despite less sedation.
Answered 7/26/2019
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