Can alcohol be used on a staph infection?

Can be or should be?: It sure can be, but it won't help much! :) topical alcohol won't do much for a cellulitis (which is bacterial infection under the skin), and a shot of whiskey probably won't help much either. Best to see your doctor for antibiotics.

No: I assume you are talking about topical alcohol (rubbing alcohol) on top of the infection. Alcohol causes tissue damage, and hydrogen peroxide or betadine is a better cleansing agent for skin infections, followed by a topic antibiotic ointment. If it is a severe infection, you may need oral antibiotics (or even iv). See your doctor if the infection is worrying you.