A member asked:

Does it matter if i take simvastatin in the morning or at bedtime?

2 doctors weighed in across 2 answers
Dr. Irv Loh answered

Specializes in Cardiology

Slightly: Because cholesterol synthesis is maximal around midnight if your sleep pattern is normal, and maximal onset of action with Simvastatin is a few hours after taking it, there is a few percentage points benefit for taking it in the evening. Long acting statins (atorvastatin & rosuvastatin) are less impacted by time of day.

Answered 10/4/2016

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When to take statin: Best time to take statins which is a medication for cholesterol is one hour before dinner.

Answered 5/8/2013

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