What kinds of damage does streptococcus pyogenes cause to the human body?

Strep complications: Streptococcus pyogenes, the bacterial cause of "strep throat", can invade other organ systems and cause infection in in areas around the tonsils, lymph glands in the neck, middle ear, mastoid regions, sinuses, bones, lungs (pneumonia), kidneys and liver (toxic shock syndrome). The noninfectious complications include rheumatic fever, rheumatic heart disease and acute glomerulonephritis (kidneys).