A member asked:

What effect does hemolysis have on the red blood cells?

4 doctors weighed in across 2 answers

Loss of cells: Hemolysis, by definition is lysis, breakdown, rupture of red blood cells. Hemolysis causes loss of hemoglobin. Depending on the rate of hemolysis red cell count may go down.

Answered 1/15/2020

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Breakdown: Hemolysis is a breakdown in the redblood cells freeing hemoglobin to present as free serum hemoglobin. Such a product may secondarily affect the kidney causing impained function and rise in creatinine. FDA will cancel a trial where a drug such as a cancer mAb induces hemolysis.

Answered 6/21/2015

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