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A member asked:
What is cause of the lack of hair in people with progeria?
4 doctors weighed in across 2 answers
Lamin A/C mutation: Different mutations within the lamin a/c gene cause different genetic disorders. Lamin a/c is needed to provide stability to the cell. With the particular mutation found in progeria, skin and hair (along with other systems) get damaged. Though i'm not sure, i suspect that rapid cell division makes skin and hair more likely to get damaged sooner from this particular lamin a/c mutation.
Answered 9/7/2020
5.7k views
Progeria: I agree with Dr. Lewy-Weiss. Point mutations within the LMNA gene are the cause of Progeria. The LMNA gene makes Lamin A, a protein which is found the nucleus of the cell and which keeps cell integrity intact. Without it there is cellular damage, tissue damage & then organ damage.
Answered 9/8/2020
46 views
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