You can: Loratadine & Cetirizine are both in a class of medications known as non-drowsy long acting anti-histamines. Although they are in the same class, i still have patients that experience drowsiness (usually more from cetirizine); however, i would try it because everyone responds differently to the same medications. Take it before bed so if drowsy you can go to sleep anyway.
Answered 3/6/2016
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Fexofenadine less : Loratidine has 8% sedation and Cetirizine 13%, so the latter is not actually permitted by the fda to advertise that it is non-sedating. In practice, i agree, responses vary. Fexofenadine is less sedating (2%) than either, but some patients claim even it sedates. If the antihistamine is for nasal allergies, prescription topical antihistamines are less sedating than oral (but cost more).
Answered 10/24/2017
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