A member asked:

What is the dose of folic acid to prevent all fetal malformations?

3 doctors weighed in across 2 answers

400 ug: This is the minimum dosing for routine pregnancy without any other circumstances that might require more such as elevated homocysteine, twins, or history of neural tube defect.

Answered 7/8/2012

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Dr. Nikolaos Zacharias answered

Specializes in Maternal-Fetal Medicine

5 mg.: Most of the severe (not all) fetal malformations can be prevented with preconceptional Folic Acid (for at least 3 months before conception). Expect 75% of cardiac defects and >90% of neural tube defects to be prevented thus.

Answered 9/11/2014

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