Yes: Neonatal lupus depends on antibodies transfered across the placenta to the baby. Sometimes the mother has the antibodies but does not have clinical disease. The antibodies cross the placenta and cause the lupus in the baby even if the mother never had identified disease. The clinical picture can include rash, heart block, low platelets. The heart occur before delivery and may need a pacemaker.
Answered 5/15/2013
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