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A 48-year-old member asked:

interstitial cystitis -- what is it?

7 doctor answers14 doctors weighed in
Dr. Lester Thompson
Pathology 33 years experience
Bladder inflammation: The bladder has several layers, starting from the lining, through the muscle to the serosa (outer lining). The "interstitium" is between the muscle bundles. An inflammation of this area, results in "cystitis". It does not mean an infections, but it often is.
Dr. Andrew Villa
Specializes in Obstetrics and Gynecology
Painful Bladder: Ic is a condition that has multiple symptoms. Most common symptoms are frequent urination, urinary urgency and pain in the bladder and pelvic area. There is no definitive test to diagnose ic, but there is usually inflammation of the lining of the bladder that produces the symptoms. Treatments include dietary changes, medication, and possibly bladder instillation of various compounds.
Dr. George Klauber
Specializes in Pediatric Urology
I agree. Bladder hydrodistention is sometimes very therapeutic.
Aug 16, 2012
Dr. Laurence Badgley
General Practice 53 years experience
Autonomic Disorder: Interstitial Cystitis, IC, as Dr. Villa stated.  I had two patients with IC, both w. sacroiliac joint, SIJ, hypermobility & chronic low back pain. After SIJ fusion symptoms resolved. Medical literatures states that 10-30% persons w. chronic low back pain have non-inflammatory primary SIJ disorder. I posit that IC is caused by SIJ laxity & pelvic presacral plexus parasympathetic irritation.
Dr. Laurence Badgley
General Practice 53 years experience
Provided original answer
IC: Amongst my industrial injury clients have been females whose IC symptoms remitted after they had surgical fusion of a disordered & hypermobile sacroiliac joint caused by lifting and slip & fall injuries; diagnosed & treated via Occupational Disabilities Guidelines, ODG, criteria.
Aug 28, 2015
Dr. Ed Friedlander
Pathology 44 years experience
Pathologic lesion: There are distinctive anatomic changes in the vessels and mast cells in the bladder, going deep into its wall. We pathologists have been slower to understand and charaterize these than we have with other lesions, and we hope that eventually this puzzling disorder can be explained and some effective treatment found.
Dr. Kevin O'neil
Urogynecology 28 years experience
IC/Bladder Pain : Interstitial cystitis is also now referred to as bladder pain syndrome. There is a decrease in, or absence of, a 'slime layer' in the bladder, which normally protects the bladder from being irritated by urine. It can be diagnosed in several ways. For most people, using a bladder pain questionnaire is a good start. A cystoscopy may show glomerulations (bleeding) or in advanced ic, hunner ulcers.
Dr. Phillip Porch
General Practice 40 years experience
Lining breakdown: It is a condition thought to be caused from the breakdown of the gag layer in the bladder. It is associated with frequency and pain in the bladder.
Dr. Stephen Rodrigues
A Verified Doctoranswered
A US doctor answeredLearn more
Trigger points!!: This is a new look at an old idea. Janet g. Travell, md a pain pioneer concluded that chronic tissue pain was caused by numerous trigger points in muscle fibers causing the muscles to contract compressing nerves, vessels and alter the flow of lymphatics. The pyramidalis and pelvic floor muscles are the cause. So this is a mechanical cause and requires a manual treatment. Acupuncture! see files.

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A 21-year-old member asked:

Is interstitial cystitis fatal?

1 doctor answer4 doctors weighed in
Dr. George Klauber
Specializes in Pediatric Urology
No: Can be very unpleasant and would only be fatal if subject committed suicide.
CA
A 21-year-old member asked:

Who develops interstitial cystitis?

2 doctor answers7 doctors weighed in
Dr. Phillip Porch
General Practice 40 years experience
Both men and women: It has a tendency to run in families which suggests a genetic factor. It is diagnosed more commonly in women.
A 21-year-old member asked:

How is interstitial cystitis diagnosed?

2 doctor answers3 doctors weighed in
Dr. Alfredo Nieves
Gynecology 40 years experience
IC diagnosis: By history and physical exam, negative urine cultue, pain relief with instillation of local anesthetic in the bladder and cystoscopy.
A 21-year-old member asked:

Is interstitial cystitis progressive?

2 doctor answers6 doctors weighed in
Dr. Alfredo Nieves
Gynecology 40 years experience
Ic: If not treated properly could be progressive.
India
A 23-year-old member asked:

Is interstitial cystitis usually fatal?

1 doctor answer4 doctors weighed in
Dr. Phillip Porch
General Practice 40 years experience
No: Interstitial cystitis while possibly affecting the quality of life due to pain and frequent urination does not cause death.

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