A member asked:

What are the side effects associated with protopic?

3 doctors weighed in across 3 answers

Rare: Protopic was felt to be superior to topical steroids for the long term treatment of eczema. Protopic reduces the skin's immune response which decreases the inflammation which is seen in eczema. Protopic (tacrolimus) taken systemically, typically in organ recipients, can increase the risk of certain malignancies. This does not apply to the small amount applied to the skin.

Answered 6/30/2014

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Dr. Paul Williams answered

Specializes in Allergy and Immunology

Stinging: The most common side effect associated with the use of Protopic ointment is stinging or burning after application. Ingestion of this medication is associated with suppression of the immune system and cancer, it is used to suppress organ transplant rejection. It is not likely that this would occur with use on the skin, but safety studies are underway.

Answered 11/30/2016

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Dr. Paul Williams answered

Specializes in Allergy and Immunology

Skin burning: If you are talking about the ointment, the most common side effect is mild burning of the skin for a short while after use. This drug has not been approved for use in children under age two.

Answered 9/22/2016

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