A member asked:

Does anyone know about the long term side effects from adriamycin (doxorubicin)?

4 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Possible AE's: May include infertility, heart dysfunction, bone marrow insuficiency, a second malignancy ( leukemia) - which may develop years after treatment has ended.

Answered 6/21/2012

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Dr. Michael Engel answered

Specializes in Pediatric Hematology and Oncology

Anthracyclines....: All carry with their use risks for secondary malignancy, particularly acute myeloid leukemia. Likewise, there is a risk of myocardial damage, and this risk increases with cumulative dose (in doxorubicin equivalents). Infertility is also a risk, where risk also increases with dose. Because of these significant, long term adverse events, we monitor cumulative anthracycline dose and limit exposure.

Answered 9/4/2013

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