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A member asked:
When is an osmotic fragility test indicated?
A doctor has provided 1 answer
Her it is: Osmotic fragility measures red blood cell (rbc) resistance to hemolysis when exposed to a series of increasingly dilute saline solutions. The sooner hemolysis occurs, the greater the osmotic fragility of the cells. Purpose to aid diagnosis of hereditary spherocytosis to supplement a stained cell examination to detect morphologic RBC abnormalities.
Answered 6/25/2022
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