What are the major presenting symptoms of rheumatoid arthritis?

Usually....: Primarily joint pain followed by visible signs of inflammation, such as redness or swelling. The diease tends toward symmetry and the most common joints involved in your upper extremity are the knuckles, and wrists and in the lower extremity, the ball of the feet (mtps), and ankles. The condition is usually progressively additive, meaning more joints involved in time. All joints can be affected.