What's the least invasive way to test for duodenal ulcer? my symptoms point to it, but i have conditions that make sedation risky do want to avoid it.

Barium x-ray: You may wish to discuss having a barium x-ray of your upper GI tract, if you do not wish to undergo sedation for an upper endoscopy which would be the better test.

Upper GI: Endoscopy, as you likely know, is the best way to diagnose duodenal ulcer. The second best way is an upper gastrointestinal (UGI) x-ray using swallowed barium sulfate as a contrast agent. The latter does not require sedation.