Cardiac output: is stroke volume times heart rate. if stroke volume goes down more than heart rate goes up, cardiac output won't increase. stroke volume depends on preload (filling of the heart), afterload (resistance to flow), and contractility (how much the heart pumps for how much it is filled. For instance, if the heart rate goes up but the the heart doesn't have time to fill, output won't increase.
Answered 3/29/2015
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