A 35-year-old member asked:
Why can't dopamine cross the blood brain barrier?
1 doctor answer • 3 doctors weighed in
Neurology 22 years experience
Biochemistry: Actually this why we give patient Levodopa-Carbidopa together, or SINEMT.
Dopamine just as molecule can not, but Levo can.
Levodopa is a prodrug that is converted to dopamine by DOPA decarboxylase and can cross the blood-brain barrier.
1.1k viewsReviewed >2 years ago
A 37-year-old member asked:
What are the advantages of a drug that can cross the blood brain barrier?
1 doctor answer • 1 doctor weighed in
Psychiatry 32 years experience
BBB: It can reach its target in the brain to exert effect, such as some antibiotics to treat bacteria in the brain.
3k viewsAnswered >2 years ago
Last updated Aug 29, 2018
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