A member asked:

Which parts of the brain are affected by ketamine?

9 doctors weighed in across 3 answers

Complicated: but the hippocampus and cortex are both effected. It can cause dissociation and over excitement. It odd a common drug of abuse, but is also used for anesthesia, depression and chronic pain

Answered 11/28/2017

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Dr. Paul Grin answered

Specializes in Pain Management

Ketamine: is a NMDA receptor antagonist as potential analgesics in the management of chronic pain. It inhibits a neural communication between the thalamus and the cerebral cortex as a general anesthetic agent. Long-term abuse can lead to paranoia, depression and in high doses can cause unconsciousness and death.

Answered 2/2/2015

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Ketamine: Ketamine acts on NMDA receptor )N-Methyl-D-aspartate receptors). They are present throughout the cerebral cortex and are also present in the hippocampus. However, its known that glutamate receptors are diffusely present throughout at least half of all neural tissue.

Answered 12/20/2014

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