A 37-year-old member asked:
Disclaimer

What chromosome is mutated in sickle cell disease?

1 doctor answer
Dr. Joseph Torkildson
38 years experience in Pediatric Hematology and Oncology
11: The beta globin gene is mutated in sickle cell anemia; it is located on chromosome 11.
Answered on Jun 18, 2017

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
Unlimited visits
$10/month

Related questions:

A 30-year-old member asked:
Dr. Jay Park
Dr. Jay Park answered
49 years experience in Pediatrics
Chromosome No. 11: Point mutation at beta-globin gene located at chromosome no. 11 results in production of defective hemoglobin, sickle hemoglobin.
2
2 thanks
A 40-year-old member asked:
Dr. Michael Dugan
Specializes in Hematology
There are: Huge ranges of disease severity and associated symptoms. Careful choices and attention to medical recommendations will improve the prognosis.
A 52-year-old member asked:
Dr. Martin Raff
55 years experience in Infectious Disease
Not much: Sickle cell disease is seldom subtle. Patients have intermittent periods of intense pain, often in bone, they have all manifestations of profound ane ... Read More
1
1 thank
A 47-year-old member asked:
Dr. James Ferguson
45 years experience in Pediatrics
Yes: The defect of sickle cell anemia occurs when 2 sickle cell genes are passed to a newborn. Since each parent passes half their genes at conception & it ... Read More
2
2 thanks

90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more. Get help now:

Ask doctors free
Personalized answers
Free
Talk to a doctor
Unlimited visits
$10/month