What are the tests for sjogren's syndrome?

Inflammatory markers: One screens for systemic inflammation - esr, CRP - plus immunologic markers. Latter includes an ANA test (usually positive in most, with speckled pattern), blood complement levels (for activity), and sjogren's tests (ssa and ssb) are often helpful - positive in about 2/3. Also may require opthalmologic evaluation for dryness or damage and sometimes a biopsy or the oral mucoal glands can help.

A few tests: Generally, checking labs is helpful since patients with sjogren's almost always have one of two autoantibodies (ssa, ssb) present. Ssa, ssb also present in lupus but when only ssa or ssb is pos, sjogren's is a top consideration. Doctors can also test for sicca symptoms(decreased tear production with a paper strip put on lower eye lid.Most definitive test is minor salivary gland biopsy from lip.